Peroxiredoxins in Redox Relay

Authors

  • Robert Z. Hopkins AIMSCI Research Institute, P.O. Box 37504, Raleigh, NC 27626, USA

Keywords:

Antioxidants, Cell signaling, Peroxyredoxin

Abstract

Peroxyredoxin  (Prx) is one of the three major defenses against hydrogen peroxide toxicity, with the other two being catalase and glutathione peroxidase. Prx represents a family of enzymes that currently include 6 members, namely, Prx 1–6. In addition to their classical function in hydrogen peroxide detoxification, some Prx isozyme may also function as signaling molecules. This ROS Research Highlights article summarizes some recent key research findings on Prx-mediated redox signaling, pinpointing certain Prx isozymes as signaling antioxidants.

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Published

2017-05-01

How to Cite

Hopkins, R. Z. (2017). Peroxiredoxins in Redox Relay. Reactive Oxygen Species, 3(9), 184–188. Retrieved from https://www.rosj.org/index.php/ros/article/view/93

Issue

Vol. 3 No. 9 (2017)

Section

RESEARCH HIGHLIGHTS

License

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