Superoxide Dismutases in Biology and Medicine: Essentials and Recent Advances

Authors

  • Ben D. Little American Institute of Innovative Medical Sciences and Technologies, P.O. Box 37504, Raleigh, NC 27626, USA
  • Robert Z. Hopkins American Institute of Innovative Medical Sciences and Technologies, P.O. Box 37504, Raleigh, NC 27626, USA

Keywords:

Epigenetics; Gene regulation; Peroxidase; Redox signaling; Superoxide dismutase; Superoxide toxicity; Tumorigenesis

Abstract

Superoxide dismutases (SODs) are a family of enzymes catalyzing the dismutation of superoxide to hydrogen peroxide and molecular oxygen. SODs are among the most extensively studied antioxidant enzymes in mammalian systems. This article provides an overview on the basic biochemistry and molecular regulation of SODs and summarizes recent cutting-edge research findings on their biological functions as well as implications in health and disease.

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Published

2020-01-01

How to Cite

Little, B. D., & Hopkins, R. Z. (2020). Superoxide Dismutases in Biology and Medicine: Essentials and Recent Advances. Reactive Oxygen Species, 9(25), 13–21. Retrieved from https://www.rosj.org/index.php/ros/article/view/253

Issue

Vol. 9 No. 25 (2020)

Section

REVIEW ARTICLES

License

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